Several manifestations of poor liver function:

1. The whole body is weak, easy to feel sleepy, always can’t wake up;

2. The eyes and skin are yellow, there are liver palms on the hands, and spider haemorrhoids on the chest;

3. Grumpy, easy to get angry;

4. The gums are bleeding, and the nose is bleeding and the skin is purple;

5. The nails have vertical lines;

6. Body fluids and urine are yellow;

7. There are pimples on the forehead and large pores.

So how to nourish and protect the liver?

1. Drinking more water is needed to nourish the liver and protect the liver

Drinking more water can replenish body fluids, enhance blood circulation, and promote Xincheng metabolism. Drinking more water can also promote the secretion of glands, especially digestive glands and body fluids and bile, so as to facilitate digestion, absorption and elimination of waste, and reduce the damage of metabolites and toxins.

2. Pay attention to diet balance

Don’t overeat or often starve. This often hungry and uneven eating habit will cause abnormal digestion and secretion, leading to liver dysfunction. Therefore, the diet should be balanced, and the proportion of protein, carbohydrates, fat, vitamins, minerals, etc. in food should be maintained: eat as little spicy food as possible, and eat more fresh vegetables, fruits, etc.

3. Nourishing the liver, protecting the liver and drinking less alcohol

The liver’s ability to metabolise alcohol is limited, and frequent alcoholism can seriously damage the liver.

According to medical research, healthy people weighing 60kg can only metabolise 60g of alcohol a day, that is, 1 amount. If the limit is exceeded, it will affect liver health and even endanger life.

4. Keep a good mood

An optimistic attitude is an important factor in maintaining health. Because the liver is happy and depressed, anger and anger can easily lead to liver qi and blood stasis, which has become a disease for a long time. If you want to have a strong liver, you should first learn to control anger. Even if you are angry, don’t be angry for more than 3 minutes. You should try your best to be calm, optimistic, cheerful and carefree, so that the liver fire will be extinguished and the liver qi will be normal and in good mood.

5. Moderate exercise

Do more outdoor sports. For example, walking, hiking, playing ball games, Taijiquan, etc.; it can not only make people’s blood flow smoothly, promote vomiting, strengthen the body, but also nourish the liver and achieve the purpose of liver protection and health care.

6. Liver-friendly food

You can eat more goji berries to nourish the liver and protect the liver. Goji berries have the effect of nourishing yin and yang, nourishing the liver and improving eyesight, improving immunity, and delaying ageing. In 2002, it was listed as a dual-use item by the Ministry of Health.

Research shows that more than 20 kinds of polysaccharides, 11 kinds of monosaccharides, and 18 kinds of amino acids were identified from Ningsia goji berries. Goji berries are rich in carotenoids. 18 kinds of carotenoids have been detected from goji berries, including 11 kinds of carotenoids and 7 kinds of free carotenoids. Among them, the largest content is zeaxanthin di palmitate, accounting for about 40% of the total amount of carotenoids. 18 kinds of trace elements and more than 30 kinds of volatile oils were detected from Ningsia wolfberries.

6-1 Ingredients and mechanism of liver nourishing and protecting liver in goji berries

The liver is the main place for human food absorption and transfer, but it is easily damaged by drug stimulation. The study found that goji berries have the effect of nourishing and protecting the liver, and its main effect is wolfberry polysaccharides (18. 50%), beetine (0. 08% ～ 2. 24%), carote (0. 173%), chlorocid (0. 023 7% ) etc.

6-2 Goji berry polysaccharides nourish the liver and protect the liver

Wolfberry polysaccharide (LBP) has a protective effect on both alcoholic liver injury and chemical liver injury. Research shows that LBP can reduce the content of alanine aminotransferase (ALT) caused by carbon tetrachloride and the lipid peroxidation level of liver cells. At the same time, LBP also helps to balance the malonaldehyde content in the body and improve the energy reserve function of the body. The main mechanism of action may be due to LBP. It has a detoxifying effect, can promote the synthesis of stem cell protein and the recovery of liver cell function, and has a certain preventive and protective effect on liver damage caused by carbon tetrachloride. LBP not only has a protective effect on chemical liver damage, but also has a good protective effect on alcoholic liver damage.

In the experiment, the rat was given gastric ethanol drink, and a rat model of alcoholic liver disease was established. After continuously giving 25w of ethanol, the LBP high-dose group (1 000mg/K song) and the low-dose group (250mg/K song) were compared with their tissue changes under an electron microscope. The high-dose group has significant differences and shows good results.

The mechanism of action may be because LBP regulates the morphology of mitochondria in liver tissue cells and delays the degree of inflammation and necrosis and the lipids of liver cells.

Degeneration, so it has a protective effect on alcoholic liver injury. In addition, it was found that HepG2 cells of human liver cancer HepG2 cells with different effects on LBP at different times and concentrations of LBP were found to destroy HepG2 cell membrane structure and inhibit tumour growth and proliferation.

6-3 Mechanism of alkaloids to nourish and protect the liver

The betaine isolated from goji berries is a quaternary ammonium alkaloid, which can inhibit fatty liver because it promotes fat metabolism. At the same time, it can reduce the levels of sorbitol dehydrogenase and alanine transaminase released by damaged cells caused by chemical and alcoholic liver injury, and play a role in protecting the liver.

6-4 Carotenoids nourish the liver and protect the liver

Goji berries contain many kinds of carotene, including free carotenoids and esterified carotenoids. Among them, the high content of free carotenoids is zeaxanthin and β-carotene. The esterified form of carotenoids in goji berries can be hydrolysed to form free carotenoids, which is easy to be absorbed by the human body, so as to quickly play its active function.

Goji berries have the effect of protecting the liver and protecting the liver, mainly because the active ingredients in goji berries can regulate lipid metabolism and lipid synthesis in the liver, which improves the metabolic function of the liver. There are also studies that show that the protective mechanism of goji berries on liver damage caused by chemical substances may be closely related to its antioxidant effect and regulation of cytochrome gene and protein expression/

6-5 Efficacy ingredients and mechanism of action in wolfberry

The essence of the liver and kidney is nourished by the liver and kidney, and the essence of the liver and kidney is nourished by the eyes. Research shows that the active ingredients of goji berries are mainly goji berry polysaccharides and carocarotenoids. LBP has a certain preventive and protective effect on macular degeneration, glaucoma, cataract, retinopathy and other eye diseases, and is also widely used in the prevention of myopia.

The laboratory used different concentrations of LBP solution to act on the retinal pigment epithelial cell damage model, and found that there were significant differences in apoptosis and growth of each group of cells. It was speculated that its mechanism of action may be related to affecting cell membrane potential and mitochondrial reactive oxygen. Further research shows that LBP has the function of regulating the self-recovery of retinal pigment epithelial cells, which can improve the removal ability of lipofuscin and its own proliferation function, indicating that LBP has a potential therapeutic effect on macular degeneration. LBP is also effective in preventing and treating diabetic retinopathy.

Guangdong laboratory has established a retinal light injury model. The results of dark flash retinal electrogram examination and retinal histopathology show that LBP has a preventive effect on diabetic retinopathy. Wang Jihong and others conducted a relatively in-depth study on it. LBP was performed on diabetic rats [200 mg (kg·d) induced by streptococcus, and the expression of each group of rats was detected by immunohistochemical staining and greyscale value, real-time fluorescence quantification and immunoblotisation, and the expression of each group of The vascular permeability of the retina of rats was detected by method. The results showed that LBP can reduce the cell permeability caused by high sugar and play its protective role.

The corn yellow matter extracted from goji berries is considered to be the main component of the eye-catching effect. The total amount of corn yellow matter in goji berries is more than 1,000 ng/g, and its content is more than 40 times that of yellow corn. The main reason is that corn yellow matter can effectively relieve the aporetinised epithelial cell Death can also improve autoimmunity and effectively prevent senile macular degeneration.

Conclusion: Goji berries have a good nourishing liver and kidney function, but the single flavour is relatively weak, and it is often used in combination with other prescriptions.

Taking the Selected Dictionary of Traditional Chinese Medicine Prescriptions as a source of information, a large number of information related to nourishing liver and eyesight have been screened, and more than 60 liver nourishing and eyesighting prescriptions related to wolfberries have been investigated. The frequency analysis of 120 multi-flavour drugs in these prescriptions shows that wolfberry and chry In the higher drug group, most of them are wolfberries and unjust silk, chrysanthemum, ripe Dihuang, yam, etc.